Rabbit Monoclonal Antibodies
نویسندگان
چکیده
منابع مشابه
Monoclonal Antibodies
SUMMARY Monoclonal Antibodies are identical antibodies and Can be generated in ultimated amounts by countinuos cultures of single antibody- secreting cells. These cell lines are produced by cell fusion of normal lymphocytes to cells of a myeloma tumor cell line, which confers on the antibody producing hybrid cell, immortality and the ability grow as atumor in animals. monoclonal antibodies c...
متن کاملAnatomic Pathology / RELIABILITY OF RABBIT MONOCLONAL ANTIBODIES Rhodes et al / RELIABILITY OF RABBIT MONOCLONAL ANTIBODIES
The reliability of the rabbit monoclonal antibodies SP1, SP2, SP3, and 4B5 was immunohistochemically assessed on a range of 96 invasive breast and carcinomas and the results compared with those achieved with established antibody markers for estrogen receptors (6F11), progesterone receptors (PgR636), and HER2 (polyclonal A0485 and clone CB11), with HER2 status validated by fluorescence in situ h...
متن کاملHigh-Affinity Rabbit Monoclonal Antibodies Specific for Amyloid Peptides
Antibodies that specifically bind to either amyloidpeptide (A ) isoform A 40 or A 42 contribute to the study of Alzheimer’s disease (AD) pathology and to the development of cerebrospinal fluid-based tests for the probable diagnosis of AD. Polyclonal rabbit anti-A antibodies possess high affinity and specificity, but their generation requires a long immunization period, and the resulting antibod...
متن کاملDevelopment of monoclonal antibodies to rabbit ocular mucin.
Monoclonal antibodies against rabbit ocular mucin (ROM) and porcine stomach mucin (PSM) were developed to explore the biosynthesis and functional significance of ocular mucin. A nitrocellulose-based dot enzyme-linked immunosorbent assay (ELISA) was developed for hybridoma screening and mucin quantitation. The sensitivity was found to be at the level of 1 ng mucin per dot, which was about 1000 t...
متن کاملMonoclonal antibodies to rabbit liver cytochrome P450 LM2.
The mixed-function oxidases containing cytochrome P450 are the primary systems that metabolize xenobiotics including drugs and carcinogens and endogenous substrates such as steroids [l-3]. The mixed-function oxidases may be key determinants of the rates of drug metabolism [2] and carcinogen susceptibility [3-S]. A major class of carcinogens to which humans are exposed is the polycyclic aromatic...
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ژورنال
عنوان ژورنال: American Journal of Clinical Pathology
سال: 2005
ISSN: 0002-9173,1943-7722
DOI: 10.1309/nr8hn08gdpvemu08